NATURAL HISTORY OF A MOUSE MODEL OF X-LINKED MYOTUBULAR MYOPATHY

Natural history of a mouse model of X-linked myotubular myopathy

X-linked myotubular myopathy (XLMTM) is a severe monogenetic disorder of the skeletal muscle.It is caused by loss-of-expression/function mutations in the myotubularin (MTM1) gene.Much of what is known about the disease, as well as the treatment strategies, has been uncovered through experimentation in pre-clinical models, particularly the Mtm1 gene

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Holiness and Patronage in the Hispanic World in the Modern Age

On March 23, 1630 the Congregation of rites issued a decree on the patron saints that limited their choice to the canonized.In this way direct control was granted to the Holy See.The choice of the cities of their patron saints in the modern age was determined Dog Food- Dry by the interests of their ruling classes, the popular devotion and by the po

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